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Schizophrenia is Associated With an Aberrant Immune Response to Epstein–Barr Virus

Discussion in 'Other Health News and Research' started by Jackb23, Jan 12, 2019.

  1. Jackb23

    Jackb23 Senior Member

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    Individuals with schizophrenia had marked elevations in the levels of antibodies to EBV virions as compared to the control population. Further analyses indicated increased levels of reactivity to EBV-viral capsid antibody (VCA) but not to EBV nuclear antigen-1 (EBNA-1) or to other human herpesviruses. Western blot analysis confirmed increased reactivity to VCA proteins in the group of individuals with schizophrenia and documented a lack of increased levels of antibodies to EBNA-1. Genetic analyses indicated an additive effect of increased levels of antibodies to EBV virions and genetic susceptibility to schizophrenia, with individuals with elevated levels of both type of markers having a greater than 8.5-fold odds of a schizophrenia diagnosis.

    https://academic.oup.com/schizophre...schbul/sby164/5193713?redirectedFrom=fulltext
     
    Lisa108, Hufsamor, Archie and 7 others like this.
  2. Archie

    Archie

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    That interesting, EBV seems to connected to so many health issues, even schizophrenia.
     
  3. Wolfcub

    Wolfcub Senior Member

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    It would be good if a true physical cause could be pinned down for schizophrenia....and the hope of a cure?
    I have probably missed something, but have anti-virals been tried for those cases?
     
  4. Archie

    Archie

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    Wolfcub likes this.
  5. Wolfcub

    Wolfcub Senior Member

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  6. Archie

    Archie

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    No problem Wolfcub, i suspect persons with Schizophrenia have their body chemistry just so wrong. Some people who have taken too much drugs can go Schizophrenic also, so maybe when the body bio-chemical balance is just totally off balance/corrupted people can start have all kinds of weird symtoms like in Schizophrenia, and that EBV stirring the pot on background ?
     

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