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Ruxolitinib (JAK1 JAK2 inhibitor): remarking results on intestinal inflammation

Discussion in 'Other Health News and Research' started by Aubry, Nov 2, 2017.

  1. Aubry

    Aubry Senior Member

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    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854652/#!po=31.3333

    C respresents inflamed dentric cells of the gut before and after administration of Ruxolitinib (the purple grapes are inflamed cells). This is causing probably the abnormalities seen in the micro biome of all ME/CFS patients.Since the micro biome is more and more investigated this could be very interesting for ME/CFS as well. Prof. Meirleir will start trials in 2018 with Filgotinib (another JAK inhibitor) in his patient groups.


    Skin and intestinal GvHD responds to ruxolitinib
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  2. knackers323

    knackers323 Senior Member

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    This looks good. Following
     
  3. jaybee00

    jaybee00 Senior Member

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  4. tyson oberle

    tyson oberle Senior Member

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    tampa, florida
     
  5. tyson oberle

    tyson oberle Senior Member

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    tampa, florida
    So did Dr De Meirleir start trials yet with Filgotinib?
     
  6. Daffodil

    Daffodil Senior Member

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    so i think the HIV-related cognitive impairment probably has similar cause to our cognitive impairment. i did a google search and found that they are looking at Ruxolitinib (JAK inhibitor) as a potential treatment for HIV-cognitive impairment. I contacted a scientist, who told me some animal results look promising.

    I think this is very good news for us!
     
    Helen and JadeD like this.

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