A New Decade of ME Research: The 11th Invest in ME International ME Conference 2016
Mark Berry presents the first in a series of articles on the 11th Invest in ME International ME Conference in London ...
Discuss the article on the Forums.

Ruxolitinib (JAK1 JAK2 inhibitor): remarking results on intestinal inflammation

Discussion in 'Other Health News and Research' started by Aubry, Nov 2, 2017.

  1. Aubry

    Aubry Senior Member

    Messages:
    155
    Likes:
    180
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854652/#!po=31.3333

    C respresents inflamed dentric cells of the gut before and after administration of Ruxolitinib (the purple grapes are inflamed cells). This is causing probably the abnormalities seen in the micro biome of all ME/CFS patients.Since the micro biome is more and more investigated this could be very interesting for ME/CFS as well. Prof. Meirleir will start trials in 2018 with Filgotinib (another JAK inhibitor) in his patient groups.


    Skin and intestinal GvHD responds to ruxolitinib
    [​IMG]
     

    Attached Files:

    • C.jpg
      C.jpg
      File size:
      72.7 KB
      Views:
      1
    Sancar, S-VV, Twazzle and 6 others like this.
  2. knackers323

    knackers323 Senior Member

    Messages:
    1,444
    Likes:
    455
    This looks good. Following
     
  3. jaybee00

    jaybee00 Senior Member

    Messages:
    123
    Likes:
    145
  4. tyson oberle

    tyson oberle Senior Member

    Messages:
    119
    Likes:
    78
    tampa, florida
     
  5. tyson oberle

    tyson oberle Senior Member

    Messages:
    119
    Likes:
    78
    tampa, florida
    So did Dr De Meirleir start trials yet with Filgotinib?
     
  6. Daffodil

    Daffodil Senior Member

    Messages:
    5,147
    Likes:
    5,053
    so i think the HIV-related cognitive impairment probably has similar cause to our cognitive impairment. i did a google search and found that they are looking at Ruxolitinib (JAK inhibitor) as a potential treatment for HIV-cognitive impairment. I contacted a scientist, who told me some animal results look promising.

    I think this is very good news for us!
     
    Helen and JadeD like this.

See more popular forum discussions.

Share This Page