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Research teams find widespread inflammation in the brains of fibromyalgia patients

Discussion in 'Other Health News and Research' started by Jackb23, Oct 2, 2018.

  1. Jackb23

    Jackb23

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    PET imaging studies reveal elevated glial activation, correlation with fatigue levels

    The results from both centers found that glial activation in several regions of the brains of fibromyalgia patients was significantly greater than it was in control participants. Compared to the MGH team's chronic back pain study, TSPO elevations were more widespread throughout the brain, which Loggia indicates corresponds to the more complex symptom patterns of fibromyalgia. TSPO levels in a structure called the cingulate gyrus -- an area associated with emotional processing where neuroinflammation has been reported in patients with chronic fatigue syndrome -- corresponded with patients reported levels of fatigue. The Karolinska team's studies with the astrocyte-binding tracer found little difference between patients and controls, suggesting that microglia were primarily responsible for the increased neuro-inflammation in fibromyalgia patients.




    https://www.sciencedaily.com/releases/2018/09/180927122946.htm
     
  2. percyval577

    percyval577 Senior Member

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    Microglia account for 10-15% of all brain cells. They are quite small though.


    (Their production of nitric oxide responds to the level of manganese, eg Filipov, Seegal et al 2004)
     
    Last edited: Oct 2, 2018
    Gondwanaland and Mary like this.
  3. Countrygirl

    Countrygirl Senior Member

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    Here is a similar article on ME:


    https://www.prohealth.com/library/invasion-source-neuroinflammation-chronic-fatigue-syndrome-86580



     
    Mel9, bertiedog, Hufsamor and 3 others like this.
  4. Hufsamor

    Hufsamor Senior Member

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  5. Hufsamor

    Hufsamor Senior Member

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