Jennifer J
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I heard this on the radio yesterday, another promising study involving probiotics! (Highlighted parts were done by me.)
http://www.npr.org/sections/goatsan...-could-protect-newborns-from-deadly-infection
http://www.npr.org/sections/goatsan...-could-protect-newborns-from-deadly-infection
If you're in desperate need for some good news, look no further. Scientists in the U.S. and India have found an inexpensive treatment that could possibly save hundreds of thousands of newborns each year.
And it turns out, the secret weapon was sitting in Asian kitchens all along: probiotic bacteria that are common in kimchi, pickles and other fermented vegetables.
Feeding babies the microbes dramatically reduces the risk newborns will develop sepsis, scientists report Wednesday in the journal Nature.
For the past 20 years, Panigrahi has been working on a way to prevent sepsis.
Early on he thought probiotic bacteria might be the answer because they work well on another infection that affects preemies, called necrotizing enterocolitis. It damages the intestines.
The tricky part, Panigrahi says, was figuring out the best strain of bacteria to protect against sepsis.
"We screened more than 280 strains in preliminary animal and human studies," Panigrahi says. "So it was a very methodical process."
In the end, the one that seemed the most promising was a strain of Lactobacillus plantarum isolated from the diaper of a healthy Indian baby. So Panigrahi and his team decided to move forward with a large-scale study on thousands of babies in rural India.
They were shocked by how well the bacteria worked.
Babies who ate the microbes for a week — along with some sugars to feed the microbes — had a dramatic reduction in their risk of death and sepsis. They dropped by 40 percent, from 9 percent to 5.4 percent.
But that's not all. The probiotic also warded off several other types of infections, including those in the lungs. Respiratory infections dropped by about 30 percent.
"That was a big surprise, because we didn't think gut bacteria were going to work in a distant organ like the lung," Panigrahi says.
Now if you think about what's going on here, it almost seems counterintuitive. Remember sepsis is a bacterial infection. So the researcher are preventing a bacterial infection with bacteria.
How is that possible? "Essentially these bacteria have a whole number of health benefits that we have just started to understand in the past couple of years, says Dr. Pascal Lavoie, a neonatologist at BC Children's Hospital in Vancouver, British Columbia.
First off, these beneficial bacteria can push out harmful bacteria in the baby's gut by changing the environment or simply using up resources, Lavoie says.
The probiotic bacteria also produces a compound that strengthens the wall of the intestine. "It acts as a barrier to prevent the bad bacteria from going through the wall into the blood," he says.
And, the probiotic bacteria can jump-start a baby's immune system.
"Sepsis is such a important problem around the world," Lavoie says. "This study has huge potential."