Generally, our Ubiquinol is prescription grade from the compounding pharmacy. However, our Mito Doctor got behind in filling out insurance paperwork (ughhh - research doctors) and we've temporarily had to go back to over-the-counter supplements. I've mentioned before that Ubiquinol in the Kaneka form seems to work best for me, but everyone is different. Anyway, I'm a comparison shopper and the best place I had found the 100 mg Qunol Mego CoQ10 was at Costco. 120 pills for $34.99 (but this week they are even cheaper). So with a family with MitoD, I alone take 600 mg a day - that is 6 pills a day (one every 2-3 hours starting as soon as I wake-up until my 6 have been taken). Be careful in comparison shopping, because most places don't carry the 120 pill bottle. Make sure you are comparing apples to apples. I went to Costco today and they were on sale for $27.99 through June 17th. That's the best price I've ever seen them. In the future, if you find a good sale on Ubiquinol, I'd love to hear about it.