What exactly do you mean when you say alkaline fluids? Baking soda (bicarb) ?
I have had enormous success using my own custom electrolyte, and two dilute acids that may or may not contribute to alkalinity.
For the electrolyte, I am using 150 to 300 mg of elemental sodium in a sodium bicarbonate, together with about 600 mg of elemental potassium in a potassium citrate. I take that in about 16 oz of water on rising, and maybe two or three additional times during the day. NEVER take this with food. One hour before a meal is a minimum.
For the acids, I am taking apple cider vinegar and citric acid. I read that these help to support the citric acid cycle and help to clear acid trapped in muscle. Some sources say these act like acids, and others say they create an alkaline condition. I haven't invested the time to do research in the literature, but all I can say is that these are doing something beneficial, and I need to quantify and define that further. The vinegar in particular seems to clean out my muscles and speed recovery dramatically. I take the citric acid by using a lemon in 12 oz water, once or twice a day. I take the vinegar two tablespoons in 12 oz of water, about three times a day.
I also use d-ribose in these solutions, a single scoop, maybe six times a day.
There is a real question for me about what do I measure to know when I have taken too much of these fluids. Should I be focusing on urine or saliva pH? These are very controversial subjects, with some camps saying that your urine and saliva pH tell you nothing, and other camps saying that they are the key to many diseases. Again, I haven't searched the literature. I'm actually hiring a local biochemist to help me understand pH in the body better and to try to develop a more science-based method to track my pH and adjust it during the day.
Aside from clearing the acid from my muscle more rapidly, what I have also noticed is that the periods when I feel really bad correspond to my urine pH going very acidic. I have no idea what it means yet. Based on your D-Lactate comments, I wonder if the alkaline fluid is just neutralizing D-Lactate directly in the intestine. It does seem like a possible mechanism.
Basically I am at the beginning of this experiment, and early results have been dramatic and beneficial. I am onto something.
That's a wonderful study thanks for sharing that. BUT does anyone else find it bizarre that these researchers went to a lot of trouble to measure bacterial populations in the gut, but then did not check for D-Lactate in the blood serum? I mean if the D-Lactic acid never gets to the blood, what is the causality to the neurological symptom.
I have long-standing food intolerance issues, but one of the most shocking things I discovered as I started to get tested was that on the Cyrex labs test for leaky gut I do NOT have high LPS in the blood, which strongly suggests that I do NOT have leaky gut. I have horrible problems with wheat, which I have removed from the diet for decades. But the Cyrex test for common gluten-like food intolerances did not show a single adverse reaction for me in other foods.
Is there some way that D-Lactic acid could permeate through the gut, whereas other bacterial particles like LPS could not? What we need here is a study that shows not only high intestinal bacteria, but then demonstrates D-Lactic acid in the blood. Does anyone have references to such a study?
I don't know, I did have high lactate last time I checked. Also, I used to be very sensitive to yogurt but that may have been due to a leaky gut.
Remember that Lactate on most blood tests is L-Lactate. This is DIFFERENT than D-Lactate!! You need to order an entirely different blood test for D-Lactate.
My L-Lactate was 0.65 mmol/L (11.8 mg/dL). What was yours?