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Orthostatic Intolerance as a neurological disorder

Discussion in 'General ME/CFS Discussion' started by Andrew, Feb 10, 2015.

  1. Andrew

    Andrew Senior Member

    Los Angeles, USA
    Just pondering something here. I have orthostatic intolerance. A cardiologist explained to me that it's caused by autonomic insufficiency in response to postural change. The result being the my body does not adequately adjust my blood pressure when I'm vertical. So if the cause of all this is a problem with my autonomic nervous system, wouldn't that mean this is (at least in part) a neurological disorder?
    Valentijn likes this.
  2. CBS

    CBS Senior Member

    By definition, your doctor's explanation seems to presume an autonomic disorder as causal ("caused by autonomic deficiency"). However, there are competing theories regarding the cause of OI and perhaps distinct groups of patients with differing causes. The first alternative explanation to come to mind is low fluid volume. Fluid loading and increasing fluid intake are primarily efforts to increase volume. Vascular tone may also play a role. Fluid volume may be neurological but is not primarily autonomic and vascular tone may be autonomic but not necessarily so.
    Valentijn and Sidereal like this.
  3. ahmo

    ahmo Senior Member

    Northcoast NSW, Australia
    I haven't had OI since I got my levels of B12/folate up. My (other) neurological symptoms cleared in this same time frame.

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