Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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Odd Skin issue from B12 (?)

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by OneToughCanary, Jun 5, 2018.

  1. OneToughCanary


    I'm having good success -- finally -- with very gradually stepping my toe into getting my methylation cycle going, but a kink has appeared that is threatening to derail my progress. Here's the scoop...

    I'm taking 500 mcg of methylB12 morning and night and have *just* begun to add in about 100 mcg of methylFolate. Meanwhile (this started before I added in the MFolate but is continuing/worsening) I've had odd patches forming on my skin -- some on my arms but mostly on my face, mainly around my eyes. The patches feel like there's some sort of thick/tough spot under the skin, and there's often a tiny hole/lesion in the middle, and the patches are irritable. I've read a similar description of such a thing -- even says "especially on the face" -- for what can happen from B12 toxicity. I've had this happen before when on B12, stopped B12 and it went away. ...but I *need* my B12! It's acutely obvious from trial and error that I need this nutrient. Can anyone hep me out? Is there some other supplement I'm lacking that if supplied would keep this from happening? (I do already take a little zinc, magnesium, and potassium each day. I know potassium can be an issue with startup, but I'm not having the typical symptoms I usually get when low in least not in a big way that I would recognize.)

    Appreciative for any advice,
    alkt likes this.
  2. alicec

    alicec Senior Member

    1 mg B12 is not a big dose - it would certainly not be toxic. I'm not aware that there even is a toxic dose - extremely high doses have been given daily without ill effect.

    You may not be taking enough folate. Try slowly increasing.
    Galixie likes this.
  3. Sushi

    Sushi Moderation Resource Albuquerque

    Some of us tolerate hydroxycobalamin better than methyl. It will convert into the proportions of methyl and adenosylcobalamin that your body needs. I inject hydroxy but don't tolerate methyl. Just a thought.
    anni66 likes this.

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