• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

    To become a member, simply click the Register button at the top right.

New research suggests more problems with the Paprotka et al XMRV recombinant paper

currer

Senior Member
Messages
1,409
Hi Barb,

I think you will find some useful research here. http://www.mecfsforums.com/index.php/topic,11420.msg132022.html#msg132022
Karin's post, #4.

Also
"PCR screening for MMTV env sequences
Using standard PCR techniques, MMTV-like virus env nucleotide sequences were identified in 33 (45%) of 74 archival breast cancer specimens but were not identified in any of 29 noncancer normal breast tissue specimens"
http://cancerres.aacrjournals.org/content/70/9/3576.full

This is particularly noteworthy as the prevalence of MMTV-like virus sequences in human gestational breast cancer (cancer occurring during pregnancy or 12 months postpartum) is as high as 62% compared with 30% to 38% for sporadic breast cancers, which suggests an influence of hormones on MMTV-like viruses also in humans (18).
http://cancerres.aacrjournals.org/content/70/9/3576.full
 

barbc56

Senior Member
Messages
3,657
Hi Barb,

I think you will find some useful research here. http://www.mecfsforums.com/index.php/topic,11420.msg132022.html#msg132022
Karin's post, #4.

Also
"PCR screening for MMTV env sequences
Using standard PCR techniques, MMTV-like virus env nucleotide sequences were identified in 33 (45%) of 74 archival breast cancer specimens but were not identified in any of 29 noncancer normal breast tissue specimens"
http://cancerres.aacrjournals.org/content/70/9/3576.full

This is particularly noteworthy as the prevalence of MMTV-like virus sequences in human gestational breast cancer (cancer occurring during pregnancy or 12 months postpartum) is as high as 62% compared with 30% to 38% for sporadic breast cancers, which suggests an influence of hormones on MMTV-like viruses also in humans (18).
http://cancerres.aacrjournals.org/content/70/9/3576.full

I didn't go to the me/cfs forum for information but did a bit of research on my own. I found lots of studies so would question your assertion that this isn't being looked into.

It looks like there is indeed an association just as there is with HPV and cervical cancer. Actually I believe the second is proven to cause cervical cancer while the first is still being investigated? I need to go back and look.

As I said interesting information and I appreciated the time you spent finding this. I guess my question would be how is this related to XMRV and the study being discussed on this thread? Have I missed something? Wouldn't be the first time, LOL!!

I guess we could start another thread on this if you feel this subject needs to be discussed at greater length.

Thanks for the info.

Barb C.:>)
 

currer

Senior Member
Messages
1,409
Hi Barb,

The thread is here.
http://forums.phoenixrising.me/show...virus-in-human-breast-and-other-cancers/page2

Please add to it as I think this is an important subject, considering how the breast cancer incidence keeps climbing.
Wiki "The number of cases worldwide has significantly increased since the 1970s, a phenomenon partly attributed to the modern lifestyles. Breast cancer comprises 22.9% of invasive cancers in women[5] and 16% of all female cancers."

The link to "XMRV" is because MMTV is another retrovirus in humans whose existence is disputed.
"Mouse mammary tumor virus (MMTV) is a milk transmitted retrovirus like the HTL viruses, HI viruses and BLV. It belongs to the genus betaretroviruses." Wiki.