https://newatlas.com/blood-test-chronic-pain/54507/ I'm not sure how well it would apply to ME/CFS. I believe that my muscle aches are perceived due to modification of neurochemistry in my brain, rather than muscle or nerve network problems, so it probably doesn't show up as immune activation in my blood. The new test certainly sounds like it will have a major impact on other types of chronic pain. Someone will eventually turn this into a finger-prick sensor (or even just press against skin optical sensor?), so that people with chronic pain can get an actual numerical measurement of their pain at any time. I'm quite impressed with Australian medical research. They seem to study things that other countries ignore.