The 12th Invest in ME Research Conference June, 2017, Part 2
MEMum presents the second article in a series of three about the recent 12th Invest In ME International Conference (IIMEC12) in London.
Discuss the article on the Forums.

Name of drug we must never take?

Discussion in 'Other Health News and Research' started by Sing, Dec 27, 2010.

  1. Sing

    Sing Senior Member

    New England
    Please someone tell me the name of the drug that is commonly used in a test, perhaps an intravenous test. This may have been reported by Dr. Cheney. The effects on those with ME-CFS can be excruciating pain for days.

    I am soon to see a Cardiologist and may have a lot of tests, as my blood pressure is so low that I have passed out at times. My heart rate is usually low too. This is Neurally Mediated Hypotension. Usually I don't get into POTS but can if I simply must race at a time when my blood pressure is very low. And I am worried that he will order a test with this drug!

    If you know what drug this is, or in fact, the names of any other drugs we are at risk from, please reply.


  2. Sam Carter

    Sam Carter Guest

    Is it Persantine, Sing?

    Persantine Effect in ME Patients: Persantine
    is a chemical manufactured by Boehringer
    Ingelheim. It is employed to perform chemical
    cardiac stress testing when a patient cannot exercise
    sufficiently to stress the heart. It is a particularly
    safe medication but when employed
    with many ME patients it can cause severe
    muscle pain over the extremities and entire
    musculature. Normally this can be reversed by
    injection of an antidote but this does not always
    work in ME patients. Severe pain and fatigue
    can be intolerable and persist for minutes to
    days in some ME patients following persantine
    use. Persantine works by dilating both peripheral
    and cardiac blood vessels and causing the
    heart rate to increase as in a POTS patient.
    Obviously one major pain and fatigue factor in
    ME patients is caused by abnormal dilatation
    of peripheral blood vessels. To my knowledge,
    no testing of ME patients with persantine has
    ever been published by Boehringer Ingelheim
    or others. It is one of the reasons I believe that
    pain syndromes in ME patients are due to a
    pathological vascular physiology.

    from p5 of:

    The Nightingale Definition of Myalgic Encephalomyelitis (ME)

    Byron Marshall Hyde MD
  3. Sing

    Sing Senior Member

    New England
    Yes, Sam! Go to the head of the class!

    It vaguely occurred to me after I started the thread that Dr. Hyde had written about this, but I didn't know where to look, at least not quickly.

    Here is one of the great values of having many heads on this forum, instead of just my own.

    I hope other people will take note too, as excruciating pain is not something any of us should have to go through.


See more popular forum discussions.

Share This Page