When the 'Holiday Season' Is No Holiday at all for Those With ME/CFS
Is December getting to you? Jody Smith shares some thoughts on some of the struggles that all too often attend this time of year ...
Discuss the article on the Forums.

N acetyl cysteine

Discussion in 'General ME/CFS Discussion' started by knackers323, Dec 17, 2014.

  1. knackers323

    knackers323 Senior Member

    Messages:
    1,379
    Likes:
    404
    Has anyone had any experience with using NAC to raise glutathione?

    Did you notice any effects, how long did it take? Thanks

    I tried the search button but just went around in circles
     
  2. Valentijn

    Valentijn Senior Member

    Messages:
    14,281
    Likes:
    45,883
    I take 1200-1800mg per day and it seems to help me quite a lot with sleep and avoiding the "wired" mental state. No idea regarding glutathione, but I haven't developed MCS or severe sound/light sensitivity or intolerance to most drugs/supplements, so maybe it has helped with that.
     
    merylg and Hanna like this.
  3. Marco

    Marco Grrrrrrr!

    Messages:
    2,380
    Likes:
    3,200
    Near Cognac, France
    All I can say is that it helps me prevent crashes and also helps with heat intolerance. No way of telling if this is due to its antioxidant properties, raising glutathione or antagonising glutamate.
     
    Wayne and merylg like this.
  4. minkeygirl

    minkeygirl But I Look So Good.

    Messages:
    4,678
    Likes:
    4,652
    Left Coast
    I don't notice anything from it at 1200 mgs/day.
     
    Webdog and merylg like this.
  5. Sushi

    Sushi Moderation Resource Albuquerque

    Messages:
    15,414
    Likes:
    23,796
    Albuquerque
    Did you try the Google Site Search option within search? You can try this for NAC as there are quite a few threads.

    Sushi
     
    merylg likes this.
  6. physicsstudent13

    physicsstudent13 Senior Member

    Messages:
    590
    Likes:
    35
    US
    can you inject glutathione powder from the capsules mixed with water? I tried it but it didn't seem to have any effect at 2000mg. there is a store in florida that sells it
    I've been taking NAC to protect my liver from the medications I'm on but I hope it isn't damaging my heart/lungs as studies say
     
  7. heapsreal

    heapsreal iherb 10% discount code OPA989,

    Messages:
    8,988
    Likes:
    8,371
    australia (brisbane)

    Interesting, how safe is a capsule of glutathione to inject? I assume different quality control for capsules vs injectable.

    I guess you could use it with saline for injection, but would there be a way to sterilize it to the grade of other injectables ?

    Have me thinking now?
     
  8. physicsstudent13

    physicsstudent13 Senior Member

    Messages:
    590
    Likes:
    35
    US
    I don't know I am tired of having brain fog and exhaustion for years and contacted a doctor who offers the injections but the price was beyond what I could afford. he was offering Meyer's cocktails too which I tried 3 times I think.
    there's a company in Florida that sells the injections. I bought the glutathione from piping rock and I didn't get any clarity or lifting of brain fog from the injections or taking the pills.

    so the b12 has to be a certain brand to be effective for brain fog and energy? is piping rock good?
    I have had significant energy increase on b complex and vitamin c injections but no help in the brain fog

    isn't NAC supposed to damage the heart walls and lungs by thickening of heart walls? it throws off the body's oxygen sensing
     
    Last edited: Dec 21, 2014
  9. physicsstudent13

    physicsstudent13 Senior Member

    Messages:
    590
    Likes:
    35
    US
    I'm not sure if NAC is safe in mouse studies it destroyed the hearts or damaged the hearts and lungs of mice.
    NAC protects both the kidneys and liver. I'm having strange chest pains lately like a sore arrythmia feeling on the right side and I have tachycardia of 122 all the time some days

    I just want to regain my clarity and brain function which I lost after sleep apnea and asthma
     
    Last edited: Dec 21, 2014
  10. knackers323

    knackers323 Senior Member

    Messages:
    1,379
    Likes:
    404
    The Myers cocktail didn't do much?
     
  11. physicsstudent13

    physicsstudent13 Senior Member

    Messages:
    590
    Likes:
    35
    US
    I'm getting strange right chest pain/soreness/arrythmias, maybe I took too much EDTA or HCG? I have right bundle branch block now but that was on an EKG before I started taking NAC. It could be low calcium from EDTA?
    I don't know if this is a result of too much NAC damaging my heart??
     
    Last edited: Dec 23, 2014
  12. knackers323

    knackers323 Senior Member

    Messages:
    1,379
    Likes:
    404
    So why did you stop at three?
     
  13. physicsstudent13

    physicsstudent13 Senior Member

    Messages:
    590
    Likes:
    35
    US
    isn't NAC dangerous and damages the heart and lungs? on a mouse study it did
     
    Last edited: Dec 23, 2014
  14. Valentijn

    Valentijn Senior Member

    Messages:
    14,281
    Likes:
    45,883
    No, it's quite safe at normal doses, unless you're predisposed to cysteine-based kidney stones. It's been used long-term on HIV or AIDS patients without ill effects at doses of 1800mg per day and even a bit higher.
     
    adreno likes this.
  15. physicsstudent13

    physicsstudent13 Senior Member

    Messages:
    590
    Likes:
    35
    US
    No but in mouse studies it caused heart and lung damage and thickens the heart wall which makes the heart function poorly which is damage. I would guess in AIDS patients it is a last option.

    I had tachycardia of 125 with taking all these supplements and high doses of NAC and EDTA and ubiquinol. I'm not sure what caused it
     
    Last edited: Dec 23, 2014
  16. Valentijn

    Valentijn Senior Member

    Messages:
    14,281
    Likes:
    45,883
    And what dose were these mice supposedly taking? Do you have a link to the study which supports your claims? From what I recall, the dose has to be at least 10x higher than a typical dose for any at all damage to occur. And the long-term studies in HIV patients showed no ill effects, so it's quite unlikely it was a "last resort".
     
  17. MeSci

    MeSci ME/CFS since 1995; activity level 6?

    Messages:
    7,996
    Likes:
    12,902
    Cornwall, UK
    As for many other supplements, Examine.com have summarised research on NAC.
     
    Valentijn likes this.
  18. Wayne

    Wayne Senior Member

    Messages:
    2,948
    Likes:
    3,184
    Ashland, Oregon
    I've tried this feature several times but can't get it to work. Most recently I got a message, and found the following online (below). It's fairly gibberish to me, and don't know exactly what I can do with it. I got this message when using Firefox, and don't get any message at all in Chrome. It just spins and spins forever, without ever accomplishing anything.

    I'm seeing the error message “Unauthorized access to internal API. Please refer to https://support.google.com/customsearch/answer/4542055” when I try access Custom Search Engine results.

    This error is an indication of trying to directly access the Custom Search Engine’s internal API (‘v1element’). Please use the code snippet found in your CSE control panel. Learn more about Custom Search Element V2 setup. For programmatic access use the public CSE JSON API. ​
     
  19. Sushi

    Sushi Moderation Resource Albuquerque

    Messages:
    15,414
    Likes:
    23,796
    Albuquerque
    It stopped working recently. Hopefully it will work again after our upgrades. I think that it has been noted in the tech support section.
     
    Wayne likes this.
  20. Neunistiva

    Neunistiva Senior Member

    Messages:
    304
    Likes:
    1,565
    I posted this in another thread but I will copy it here too in case someone didn't visit the other thread: I read that it seems N-acetylcysteine (NAC) increases mercury concentrations in the kidneys and the brain so maybe people who eat fish or otherwise have elevated mercury levels should be careful with taking NAC.
     
    Wayne and TreePerson like this.

See more popular forum discussions.

Share This Page