I started taking Fludrocortisone last year and it has been really helpful for my POTS symptoms. No brain fog anymore. Feeling alive and engaging in normal life. However after about 4 months, I began to have anxiety issues and be oversensitive for almost no reason. I began taking antidepressants (Serpass, Anafranil) and (Zoloft, Lexatonil) in low doses to cover the symptoms and it helped. After about 5 months I began to be overwhelmed about the amount of medication I take a day and began to recognize that my problem could be due to low levels of potassium in my body. I decided to stop the medication and see if my POTS symptoms would come back. To my surprise, I felt almost normal for two months. Oh my God! I didn't believe that just happened. So I discontinued psychiatric drugs gradually and kept taking Serpass only. The third months, I began having some symptoms again which increased gradually. So I would take 0.1 or 0.2 dose a day for a couple of days till my symptoms go away then stop it again. And that is how I managed the third month after discontinuation. In the forth month, I found that a dose for two days was not really helping! So I took it for a little longer hoping it would alleviate my symptoms, but it didn't. So I overdosed until I got better. I began to feel good but anxiety struck again so I decided I would keep taking the medicine while taking potassium supplement (2500 mg a day) to help my anxiety symptoms go away. My POTS symptoms struck again and that time it refused to improve. I discontinued potassium (I had doubt it could be contributing to fludrocortisone being less effective) and kept taking fludrocortisone in 0.4 mg a day (a large dose I know but I was hopeless).
Can (taking Potassium tablets along with fludrocortisone) or(overdosing on fludrocortisone like 0.4 mg per day) cause the medication to be less effective?
Can (taking Potassium tablets along with fludrocortisone) or(overdosing on fludrocortisone like 0.4 mg per day) cause the medication to be less effective?