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My 23 and Me Results: Can lifestyle override genetics?

Messages
95
Hi everyone,

I just got my DNA results. I already new I have CBS pathway issues and methylation issues despite the results.

Here some of them are:

BHMT +/+
CBS: +/-
COMT: +/-
MTHFR: -/-

I have more if anyone would like to look at them. ANy suggestions will really help.

I cannot handle anything with glycine, PC, glycinate, b vitamins or sulfur foods or supplements.

I am taking: zinc, ornithine, yucca, cod liver oil, BCAA's, mangosteen, magnesium chloride, lugol's, ALC, SBI protect, barley grass . Juicing and steamed veggies for 60 days to detox and remineralize.


Though according to my results I can really use phosphyl choline to help the BHMT. But it gives me nasty headaches. It has been suggested to take it with zinc to see how I feel. I will try that.
Not sure why I can't handle any b vitamins despite my MTHFR being fine genetically. So I guess my question is can behavior determine outcomes and override genetics? I think that's what's happening with my inability to metabolize b vitamins.
 
Messages
95
Hi everyone,

I just got my DNA results. I already new I have CBS pathway issues and methylation issues despite the results.

Here some of them are:

BHMT +/+
CBS: +/-
COMT: +/-
MTHFR: -/-

I have more if anyone would like to look at them. ANy suggestions will really help.

I cannot handle anything with glycine, PC, glycinate, b vitamins or sulfur foods or supplements.

I am taking: zinc, ornithine, yucca, cod liver oil, BCAA's, mangosteen, magnesium chloride, lugol's, ALC, SBI protect, barley grass . Juicing and steamed veggies for 60 days to detox and remineralize.


Though according to my results I can really use phosphyl choline to help the BHMT. But it gives me nasty headaches. It has been suggested to take it with zinc to see how I feel. I will try that.
Not sure why I can't handle any b vitamins despite my MTHFR being fine genetically. So I guess my question is can behavior determine outcomes and override genetics? I think that's what's happening with my inability to metabolize b vitamins.
Oh I'm also GAD +/+ which can explain my glutamate issues
 

keenly

Senior Member
Messages
814
Location
UK
The worlds leading expert on mitochondria says at LEAST 85% of diseases are mitochondrial in nature. I would personally say 95%.

This means genetics are vastly overrated and your environment determines your health. My gran lived to be 95 and never went into hospital until her last week. I got ill at 16. Difference? I was on antibiotics devastating my microbiome. She was never messed with.