I finished the cycloferon i was on and just taking the famvir, 4 days ago i woke up feeling rather crappy, by the end of the day the glands in my neck were sore and im thinking, right im starting to crash, what should i do. I have a heap of valtrex which i stopped using and i smashed a couple down when i got home that night, another before bed and another when i woke up, they are 1000mg strength. I did have to take a day off work but the crash was over in 2 days and feeling ok again, which is very quick recovery time for me. What im not sure about is that when my cfs started it was with ebv as well as the chickenpox, but ever since then have tested negative to ebv since that first positive, i also have cmv as well. I did use valtrex in the past but after an initial good response, slowly went backwards after the good gains i made from famvir. Im wondering if others have tested positive to ebv (IgG antibodies as well) and then future tests, tested negative? i also wonder if ebv can sit in the nerves or brain and not show up in blood tests, thus giving a negative antibody test, or is it an immune system malfunction that my body doesnt produce ebv antibodies, but ebv is still running around holding hands with cmv causing kaos. Does anyone know if natural killer cells have anything to do with making antibodies or stimulating the immune system to make antibodies, as my nk function is quite low. Any thoughts appreciated. cheers!!!