Here I am! I got the 23andme data from my mother, and guess what: She carries exactely the same four missense mutations on her mitochondrial DNA as me, which means that: -my mutations are hereditary acquiered -they are probably existing in each of my cells These mutations are not known, which means that they probably don't ever cause early/severe clinical outcome, but each of them are stucked to 4 well known pathogenic mutations, so there is a strong probability that they cause the health problems in my mother line. It was a precious day yesterday when I received this result, because it's so important to us to understand why we do struggle so much, and when finally you get the answer, it is a real weight you lift from your chest. I wish many other PR members will find some answers here like I found mine. I especially thank @BeautifulDay and @Learner1 who put me on the right tracks, you probably saved my life. Thank you to PR and to all the members. If someone needs help to find his mito DNA mutations in his 23andme datas, I can help and give back a bit of what I was offered here.