- Messages
- 22
Starting a Methylation protocol and have some questions:
I'm taking metafolin but holding off on the b12 due to high plasma levels (900+) with normal MMA - can I continue to do this or do I need to add in a methylb12 or hydroxob12 to prevent methyl trapping?
A lab test/capsule endoscopy found inflammation in my small bowel, however, it does not seem to be related to crohns or UC of any sort.
Many sensitivity issues with foods that began after I started large quantities of green vegetables (folinic acid intolerance?)
Have random numbness in lower extremities.
Plasma amino acids that are elevated are: Valine, Cystine, Isoleucine, Leucine, Lysine, Tryptophan, Arginine, Proline
VDR BSM Taq +/+
MAO-A +/+
MTHFR C677T +/-
MTR A2756G +/-
CBS C699T +/-
CBS A360A +/-
CYP1A1*2C A4889G +/-
CYP1B1 L432V +/+
CYP1B1 R48G +/-
CYP2D6 S486T +/-
CYP2D6 100C>T +/-
GSTP1 I105V +/-
NAT2 R197Q +/-
Look at these SNPs, what other supplements can you suggest for me?
I have access to any and every lab that is offered at Mayo Clinic - what labs do you suggest I get to try to figure out what is causing my problems?
Thank you.
I'm taking metafolin but holding off on the b12 due to high plasma levels (900+) with normal MMA - can I continue to do this or do I need to add in a methylb12 or hydroxob12 to prevent methyl trapping?
A lab test/capsule endoscopy found inflammation in my small bowel, however, it does not seem to be related to crohns or UC of any sort.
Many sensitivity issues with foods that began after I started large quantities of green vegetables (folinic acid intolerance?)
Have random numbness in lower extremities.
Plasma amino acids that are elevated are: Valine, Cystine, Isoleucine, Leucine, Lysine, Tryptophan, Arginine, Proline
VDR BSM Taq +/+
MAO-A +/+
MTHFR C677T +/-
MTR A2756G +/-
CBS C699T +/-
CBS A360A +/-
CYP1A1*2C A4889G +/-
CYP1B1 L432V +/+
CYP1B1 R48G +/-
CYP2D6 S486T +/-
CYP2D6 100C>T +/-
GSTP1 I105V +/-
NAT2 R197Q +/-
Look at these SNPs, what other supplements can you suggest for me?
I have access to any and every lab that is offered at Mayo Clinic - what labs do you suggest I get to try to figure out what is causing my problems?
Thank you.