I didn't know I had terrible genes till a natural doctor I was going to put me on massive doses of b vitamins and really screwed me up. I have never had any problems taking vitamins before this but now I can't even take vitamin c, omega 3, or any b vitamins esp b6. They had me on neuromethylation cream 1 pump a day(5-mthfr (5mthyl tetrahydrofolate), hydroxycobalamin, mehtylcobalamin, pyridoxal-5 phosphate, mature vitamin d3), adaptocrine 1 tab 1 a day, progestaid(which has b12 as cynocobalamin in it, b6 p5p and other b vitamins), p-5-p 2 tabs a day. I got so sick that I felt like I had fibromyalgia and wasn't sleeping at all. These vitamins were taken in the morning. The doctor said it couldn't be the vitamins so I stopped taking them and went to an Mthfr doctor who then proceeded to put me on different vitamins. They tried same which made me very dizzy just 1 250 tablet. B-minus which has p5p, riboflavin, nicacin, thaimin, biotin, and pantothenic acid and that made my whole body hurt too. Then they tried neurocalm from designs for health and that made everything hurt it was hard to walk down the stairs and pick up plates to put them in the dishwasher. So now I don't want to go back to that doctor because after lots and lots of money and no progress I still can't take any vitamins that is vitamin c, omega 3, and magnesium. I do think I might have a sulfur/ammonia problem. My gut is very healthy because of all of the probiotics I take and by eating a very healthy diet no gluten no processed foods most of it I make myself. I also have the tests that say so. I got my mthfr done and it says I am detoxing at about 75%. I am having pain in my abdomen and rashes on my hands. I still have sleep problems but not as bad as when I was taking bvitamins and I am not in as much pain but what do I do now. I don't know where to start and I am afraid I am going to get so much worse because I don't think I am detoxing and that just seems bad. Also the vitamins the docs gave me made me feel like I had Alzheimers and it scared the hell out of me. I have hetero mthfr c677t a homo cbs a360a. homo comt v158m rs4680, homo comt h62h rs4633. I am not sure which other ones I need to try but this has been going on for almost a year and a half. I don't know what to do at this point and I would really like some direction and some hope that I will be able to take some vitamins without what seems to be overmethylation myself. Thank you so much for any help.