I'm getting headaches, upset stomach, irritability, anxiety, weak muscles/cramps, sweating and overheating. I took l methylfolate alone at 7mg for 2 weeks before reducing slowly to 500mcg a day now. Even that is messing with me. Just realized that not taking methyl b12 can cause a methyl trap. I wasn't taking it until a few days ago and I was only probably taking 100mcgs. It's the only reason I can come up with as to tonight why I could have responded so well to the folate for a while and then abruptly stopped tolerating it. Any input on if these symptoms sound right? Has something similar happened to someone?