I am not really sure if I have a folate or B12 deficiency or even something else.I get very tired at work and this comes with brain fog.I also noticed when I do suffer from fatigue there is usually a jerky like or reflex movement in my legs and sometimes fingers. Other symptoms which I have but I am now beginning to think it could all be related includes,mild panic attack, anxiety,sweatiness,social anxiety,irritability, moodiness,histamine problems (runny nose, itch eyes, PE),balance problem,speech fluency and general brain fog. Previously, I have used "Fatigued to Fantastic" and this seems to have some effect.I felt my brain was working correctly,but this effect didn't last for long. I was also concerned about the 800mc folic acid.I also noticed some improvement with Gotu Kola,found out it is rich in B Vitamins ,but read one shouldn't use it for the long term. I switched to the Thorne Research b complex #12 but noticed I was getting fatigue on this. I had a blood test done and the result shows everything was fine, the only thing there were concerned about was my high potassium. I switched to Thorne #5, but still fatigued.I remembered one day I stopped the b complex and used Acetyl-L-Carnitine and there was no fatigue. Again this effect only lasted a few days. I decided to buy some metafolin 800mcg,and B12 Methylcobalamin by Solgar and again was getting fatigued. I then decided to quit these. Few months latter, I decided to take the metafolin and to my amazement the brain was working great. There was no fatigue, mood was great, speech was great..This lasted for a week or two.I now decided to try NT Factor a supplement on iherb with 400mcg folic acid..After using this for about 7 days, I noticed the fatigue again.I have stopped taking the metafolin because of the amount of folic acid in NT Factor supplement. Today, I took Metafolin in the morning on an empty stomach and no fatgue at work and mood was great. I took Jarrows B12 Methylcobalamin at mid afternoon and there was no fatigue after lunch. What I really want to know is if my problem is folate related. How much metafolin can one take in a day? Is there any difference taking metafolin on an empty stomach ? Can one take too much Potassium? Thanks.