If this is what they can do to a confirmed Lyme disease sufferer for whom effective treatment exists, what hope is there of any of us in the UK ever getting Rituximab on the NHS? My prediction is that, however good the phase III Rituximab trial results turn out to be, the NHS are never going to pay for it to be given to ME sufferers. The struggle PWME have been engaged in for decades just to have their suffering taken seriously will be replaced by the whole new struggle of establishing entitlement to, and then getting, the treatment that can help. The state of the economy being what it is and what it looks set to be for years to come, I have a feeling that any remotely costly treatment for ME will simply never pass muster in Whitehall and therefore never make it into the bodies of PWME, who in some cases will have waited the best part of their lives just to see an effective treatment come into existence. Even when the light at the end of the tunnel is so close that it dazzles, PWME may never actually make it out of the tunnel they've been trapped in all these years.