Please comment if you have any thoughts whatsoever. Is it possible to have low adenosylcobalamin and normal mb12 levels? My nutri eval showed 0 succinic acid. Lol. If that doesnt scream ad12 deficiency i dont know what does. I also had high regular b12 blood test results from a separate test before i supplemented with any form of b12. I have ran my genes also and im not sure if any one of them is capable of showing the above scenario as a mutation or two in some gene??? I was under the impression that mb 12 efficiently converted to ad12. From my experience this does not seem to be the case at least in my body. I sesm to get some added benefit from methylcobalamin though nowhere near enough. I get heart palps majorly and blood pressure spikes if i dont take ad12 as if im going to have a heart attack. Lol. My heart checks out fine apparently aside from the symptoms otherwise. It is confusing though because my homocysteine and methylmalonic acid were great. Succinic acid nonexistent and blood serum b12 (regular lab corp blood draw test) elevated like 50 pct above the top of the reference range. Symptomatically the mb will help with some confusion. Perhaps maybe like one one hundredth of it converts to ab12 it feels like. I read online that majority of b12 is stored in the liver as adb12. Is that true? I dont think i read it in a study. Hydroxocobalamin really doesnt do anything for me. Mb12 really doesnt do a whole lot for me either. Im thinking due to the multi symptom relief i get from adb12 and my labs that i have some mutation causing adb12 deficiency. It was my understanding that if methylmalonic acid and homocysteine were good that endogenously converted methylcobalamin was working. My theory is that just my bodys conversion to adenosylcobalamin is off. Any thoughts? I can post my genetic mutations if anyone knows what specific ones i should post here.