LDN may be helping. Constipation had been a serious issue, self diagnosed SIBO-C, after serious multiple courses of antibiotics. I Started back on LDN taking it in morning, too many issues at night. Bam, things started working! I'm taking 1mg before breakfast as soon as I walk upstairs. I had booked an appointment with a gastro. I then started reading up on SIBO, came across studies for treating SIBO with LDN. Well I started back on LDN 4 days ago and for the last two days...success. Am I certain, no, but reasonably confident.