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“The JC virus is an example of an infection that specifically targets glia, the brain’s support cells,” said neurologist Steve Goldman, M.D., Ph.D., co-director of University of Rochester Center for Translational Neuromedicine and senior author of the paper. “Because this virus only infects human glia and not brain cells in other species, it has eluded our efforts to better understand this disease. To get around this problem, we have developed a new mouse model that allows us to study human glia in live animals.”
http://www.urmc.rochester.edu/news/story/index.cfm?id=4209
http://www.urmc.rochester.edu/news/story/index.cfm?id=4209