Review: 'Through the Shadowlands’ describes Julie Rehmeyer's ME/CFS Odyssey
I should note at the outset that this review is based on an audio version of the galleys and the epilogue from the finished work. Julie Rehmeyer sent me the final version as a PDF, but for some reason my text to voice software (Kurzweil) had issues with it. I understand that it is...
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If Equilibrant Works for a Patient, is there any Consensus for How Long it Takes/What Dose?

Discussion in 'Antivirals, Antibiotics and Immune Modulators' started by used_to_race, Feb 28, 2018.

  1. used_to_race


    Southern California
    Title says it all really. I've been taking Equilibrant for 10 days or so now, and my symptoms have been fluctuating, but within normal ranges I'd say. No indications yet that it's doing much. I'm up to 1/2 tablet per day, so I'd imagine it's not realistic to expect a benefit quite yet. Let's say I'm in the magical subgroup that responds to Equilibrant (I am, after all, a younger male who hasn't been sick for very long and isn't severely ill). Should I expect to see results after a month? Dr. Chia told me there's no need to go above 2 tablets per day, but I've seen people taking 6-10 tablets a day or sometimes more and only then getting results. What's the deal with this?
    perrier likes this.
  2. junkcrap50

    junkcrap50 Senior Member

    There are other posts about this, but I thought one needed to wait at least 3 months to see if there's a response. I took it for 6 months with no change and was taking 6 pills a day, because the box said 3 pills bid. After 6 months I stopped. But my understanding is that 3 months will determine if you need to keep taking it.
  3. Hip

    Hip Senior Member

    Results from oxymatrine (if you are one of the responders) will tend appear at around the 2 month point approximately. Often patients will feel worse before getting better, and feeling worse is a good sign that the immune system is starting to fight off the virus. Sometimes patients will even experience a fever for a few days, and when the fever it over, they start feeling much better.

    However, my understanding is that patients would normally increase the oxymatrine dose a little week by week, ramping up to a maximum of around 6 pills a day. So I am not sure why Dr Chia said to you that you don't need to go above 2 pills per day. Perhaps he has changed his protocol.

    Dr Chia says that if oxymatrine does work for you, continuing taking for 1 year will help avoid relapse. Ref: 1

    Here are some useful posts/threads on oxymatrine:

    Dr Chia: Oxymatrine
    Oxymatrine, Autoimmunity, ME/CFS and FM
    Quixotic: Equilibrant
    Invest in ME 2010 conference transcript
    oxymatrine effects
    immunomodulators info
    used_to_race and junkcrap50 like this.
  4. Wonkmonk

    Wonkmonk Senior Member

    Are there any accepted scientific studies that confirm the effectiveness of oximatrine (in some patients)?
  5. Hip

    Hip Senior Member

    Dr John Chia, who pioneered the oxymatrine treatment for ME/CFS, was not able to get funding for a formal clinical trial, so he did his own informal study on oxymatrine. You can read the results of the study in this post.
    sb4, used_to_race, jpcv and 1 other person like this.

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