I suddenly fell very ill with a wide range of symptoms in March 2016 - including weak/numb legs and left arm, dizzy spells, lightheadedness, orthostatic hypotension, general weakness and fatigue, digestive issues (nausea, bloating, no appetite), joint pain. I'd been suffering with bladder urgency/frequency, unexplained tiredness, hair loss, tinnitus for a few years prior to this. In April 2016 I discovered I had macrocytosis and a B12 level of 243. I have now been injecting B12 daily for 15 months. However, although a few of my symptoms have improved a little, none have resolved and I'm still feeling very unwell. I've recently had my Cortisol checked and high levels came back: Sample 1 - 16.84 (2.68 - 9.30) high Sample 2 - 15.23 (0.75 - 2.93) high Sample 3 - 3.78 (0.36 - 1.88) high Sample 4 - 0.83 (< 94) normal I have been taking holy basil for this and trying to think of ways to reduce the stress in my life or change my approach to handling it. More recently I've had my thyroid panel checked again, including my RT3 this time. My TSH has raised from around 1.4 to 3.4 in a year. My other results are below: TSH - 3.45 (0.27 - 4.2) Free thyroxine - 16 (12 - 22) T4 - 94.8 (59 - 154) Reverse T3 - 23 (10 - 24) Reverse T3 ratio - 15.51 (15.01 - 75) I think the Cortisol and high RT3 are connected and likely related to chronic long term and specific stress. I haven't been diagnosed with a thyroid condition by a doctor and do not currently medicate for it. I have access to NDT and T3 - I know it might be a battle to get a doctor to consider supporting medicating but I'm willing and able to read and research - and listen to opinions - on what I need to do to to self-medicate. I've treated a B12 deficiency, low iron and gastritis successfully. I'd be interested to know whether the above Cortisol/thyroid results could be causing or contributing to my symptoms. More importantly, I'm interested in how people would tackle this to reduce my RT3 - I know I need to work on reducing my Cortisol (suggestions aside from holy basil welcomed!) but would treating my thyroid simultaneously help towards relieving any symptoms? Thank you for any help!