drob31
Senior Member
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Here's my logic:
Being low in zinc may lower the TH1 arm of the immune system while leaving the TH2 relatively unaffected:
https://immunityageing.biomedcentral.com/articles/10.1186/1742-4933-6-9
So when you start taking zinc, the TH1 comes back online and starts attacking things that are there, things that TH2 can't quite address properly.
So when you start to correct this deficiency, you have some sort of bad initial reaction (inflammation)?
Being low in zinc may lower the TH1 arm of the immune system while leaving the TH2 relatively unaffected:
Furthermore, the TH1/TH2 balance is affected by zinc. During zinc deficiency, the production of TH1 cytokines, in particular IFN-γ, IL-2, and tumor necrosis factor (TNF)-α is reduced, whereas the levels of the TH2 cytokines IL-4, IL-6, and IL-10 were not affected in cell culture models [46] and in vivo [47, 48].
https://immunityageing.biomedcentral.com/articles/10.1186/1742-4933-6-9
So when you start taking zinc, the TH1 comes back online and starts attacking things that are there, things that TH2 can't quite address properly.
So when you start to correct this deficiency, you have some sort of bad initial reaction (inflammation)?
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