Has Suramin ever been tried on Post Ebola Syndrome?

[Jesse2233]

Had this thought the other day... I image the answer is probably yes given the wide availability of Suramin in West Africa, the prevalence of both Ebola and African sleeping sickness there, and the possibility a doctor or researcher there has intuitively or inductively connected anti-purinergic therapy to a hypometabolic state.

Since Post Ebola Syndrome may likely be ME (or a very close metabolic end result), knowing the results of potential Suramin treatment in this cohort could give us a kid of preview of Dr Naviaux's upcoming trials. Additionally, anecdotal or reported evidence could perhaps inform Dr Naviaux's dosing schedule and monitoring of side effects

Edit: Interestingly Suramin has been found to inhibit entry of the Ebola virus https://virologyj.biomedcentral.com/articles/10.1186/s12985-016-0607-2

It's unclear what if anything that portends for Post Ebola Syndrome

 

[alex3619]

I suspect there are a host of post crisis syndromes, which probably share many core mechanisms. Those core mechanisms are what I think ME, or some other term that is used, will turn out to be.

I have never read anything about the use of suramin for post ebola. One issue I think is that post ebola is a relatively new realization, we never had a major outbreak where this would be obvious until that last big one. So the useful research history is likely to be brief.

Rather than them helping us, I suspect that ME research will help them instead, though ebola is so scary they may get more research funding than we do.

 

[Jesse2233]

Yes that's probably true.

Still though, it would be interesting to ask a doctor in Monrovia or Freetown about Suramin for Post Ebola.

Has anyone ever seen any posters from West Africa on this board?