I've read a similar post from 2012, but wondering if anyone has something to add. I've had M.E. since 2008 and it's been a lot worse since 2013. This is the first prescription drug I'm thinking of trying for it (not including what I'm taking for my orthostatic intolerance) and I'm a bit nervous. It's hard to get an RX for in Canada: my doc has studied with Dr. Klimas and is suggesting her pulsing protocol. My M.E. started in 2008 with a virus. My daily symptoms are fatigue, light-headedness, brain fog, some joint pain. When I crash I get flu-like symptoms: feeling feverish (without a temp), malaise, sore throat. If I get bad reactions initially, should I quit right away? Or is that part of the process (a "die-off"?) Other posts mention NK function levels: we can't get that tested here in Canada, so I don't know what mine is. Thanks!