I thought this was an intriguing article, and expect to be giving frankincense a try soon. This particular article also has segments on acetyl-L-carnitine, curcumin, and amino acid therapy. Best, Wayne @brenda, @Vineyard1 -- [LINK to Vineyard's positive reference to frankincense] - Lyme Brain: Causes and Solutions (Oct 2015) Townsend Letter, Alternative Medicine Magazine Frankincense Essential Oil I have been utilizing essential oils more and more with my patients, and seeing great results. Essential oils, being lipid-soluble, can cross the blood–brain barrier easily and have good penetration into cells overall. There are a number of constituents that make particular oils good for neurological symptoms. Some of the key ones are sesquiterpenes, because of how easily they cross the blood–brain barrier. These help to oxygenate the tissues, reduce inflammation, and calm the nervous system. They can support the endocrine system and have analgesic effects. Some oils that are high in sesquiterpenes are cedarwood, frankincense, patchouli, vetiver, ginger, ylang-ylang, myrrh, Helichrysum, Melissa, and black pepper. Frankincense in my view is the very best essential oil for Lyme brain. So long as the highest-quality oils are used, frankincense can safely be taken internally. I have patients either put it directly under the tongue, or swallow it as a capsule or in some cases on the roof of the mouth (preferably toward the back of the mouth at the soft palate). Frankincense can also be put on the soles of the feet; the soles are a good entry point for essential oils, as the skin is quite thin, and yet the pores are the largest there of anywhere on the body, so systemic absorption is rapid and effective. Yet others apply it on the temples or the base of the skull. Patients love frankincense – it helps with brain fog, focus/concentration, and emotional balance. I have a handful of patients who have seizurelike activity that is now controlled with daily use of frankincense. I have many more who report that their brains are so much clearer since using frankincense. - Conclusion These are just some of the modalities and supplements that I use to help with the cognitive and psychoemotional symptoms of Lyme disease. There are many others that can be helpful, and we didn't even get to touch on the dietary elements! My book, Lyme Brain, due for publication early 2016, will contain much more information on how to help. Sign up to be notified when the book is published at www.LymeBrainBook.com.