Hi the title pretty much says it all. For the past two years I have been in a total state of being ramped up and nerve hyper excitability. I feel very much in the minority bc most people on the board seem to have a fatigued state. Ive posted before so sorry if this is all repeat, but mine started with 2 years ago with out of the blue adrenaline rushes in my sleep and very high adrenal feelings and symptoms almost like something was attacking all my nervous system . They tested me for some adrenal tumor and other things. When the anxiety became overwhelming from all the twitchings and head pressures and assorted goodies, I turned to a psychiatrist for help. However EVERYTHING he gave me made it all worse. I recovered for a short while (when I was told I had reactivated EBV and Lyme I then had a focus and felt less scared). But now a year later I am really questioning the validity of ALL DIAGNOSES and keep coming back to there must be something wrong with my brain and that I am brain damaged or something has infected my CNS. I am on Valcyte and feel positively poisioned. Eyes burning and twitching, sunburned face feeling, acute anxiety back, insomnia. Anything that has hydrochloride tends to make me worse. But even Klonopin and Valium didn't work. Im worried that NOTHING will take this edginess off. I feel so different than everyone which makes me wonder if docs are missing something! I do have autoimmune markers for ANA, histone and Anticardiolipin, but no rheumy will make the call that I have an actual disease. I had a spell of this for 6 months back in 1999 and then lived perfectly fine until 2013. I know autoimmune can flare and remit. At the time of that flare, I had super low c4 and a high Igm. The Igm is still in my blood today but no one can figure it out. Sorry, I just needed to vent. This is getting so hard. I am pacing and crying all day long. Maybe its lack of oxygen to my brain?