Ever since becoming ill i have some kind of exercise intolerance but i'm not sure if it's PEM. I don't become extremely tired after overdoing exercise, but i do feel really sick for a couple of days. I did some cardio last night after feeling quite ok for the past week, then this morning i did some strength training with dumbells and barbells. Within an hour after training i noticed the "attack" coming up; - Brain fog - Polyuria (frequent urination) - Above leads to pain in joints and muscles, it feels like no fluid is left in them because i peed it all out. My skin dries up as well. - Moving my muscles feels like they're loaded with lactic acid. - My eyes start to itch - Overstimulation - Anxiety attacks, racing mind, doom thinking. <-- this is really significant - Bowels start to hurt - Diarrhea - Burning feeling in lungs - Disturbed sleep - I can't cope with any form of mental stress. The strange thing is that i can counter the attack with the use of an anthistamine, a leukotriene inhibitor, symbicort and fish oil. Which all block/antagonize metabolites from mast cells. It only reliefs the symptoms by a bit but it helps. So is this a mast cell attack? Or ME related PEM?