Is this anything to worry about while taking methylfolate or methylcobalamin? I’ve been experiencing symptoms of what I assume is over-methylation, sort of a panicky, wired feeling that lasts through the day. I’m taking Seeking Health’s Active B12 methylfolate product, and I’m just trying to push through it rather than quench it with niacin or take a lower dose. I think I’ve read somewhere that excessive methyl groups leads to high levels of glutamate and that this is associated with neuro-degenerative conditions like Parkinson's and Alzheimer's. I've assumed mthfr supps are benign up until this point, and I don’t want to cause any permanent damage.