pattismith
Senior Member
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I thought that Dry vitamine E will be both a succinate donor and a vitamine E donor, both interesting for ME...
I was wrong!
Alpha Tocopheryl Succinate in Cancer Care
Just another Vitamin E?
By Tina Kaczor, ND, FABNO
Abstract
dl-alpha tocopheryl succinate (aTOS) is an analogue of alpha-tocopherol (vitamin E) with unique biological properties. Unlike its parent compound, aTOS does not have a redox potential and is therefore not an antioxidant.
Its ability to prolong cell cycle arrest, induce apoptosis, and act as a radiosensitizer make aTOS a compound of great interest in integrative cancer care. In vitro and in vivo evidence suggests it is capable of simultaneously protecting normal cells from chromosomal damage while potentiating cytotoxicity of conventional therapies. Application of aTOS to chemopreventative and cancer treatment strategies should take into account these known actions as well as conversion back to alpha tocopherol (aTOH) systemically.
(full article available and very interesting)
I was wrong!
Alpha Tocopheryl Succinate in Cancer Care
Just another Vitamin E?
By Tina Kaczor, ND, FABNO
Abstract
dl-alpha tocopheryl succinate (aTOS) is an analogue of alpha-tocopherol (vitamin E) with unique biological properties. Unlike its parent compound, aTOS does not have a redox potential and is therefore not an antioxidant.
Its ability to prolong cell cycle arrest, induce apoptosis, and act as a radiosensitizer make aTOS a compound of great interest in integrative cancer care. In vitro and in vivo evidence suggests it is capable of simultaneously protecting normal cells from chromosomal damage while potentiating cytotoxicity of conventional therapies. Application of aTOS to chemopreventative and cancer treatment strategies should take into account these known actions as well as conversion back to alpha tocopherol (aTOH) systemically.
(full article available and very interesting)