Dr Rostenberg videos on the best clear explanation I've heard of whats happening with these snp's and help to get them balanced.
http://beyondmthfr.com/2014/05/05/comt-and-mao-in-the-brain/
http://beyondmthfr.com/2014/05/07/how-to-balance-comt-and-mao-in-the-brain/
http://beyondmthfr.com/2014/05/05/comt-and-mao-in-the-brain/
http://beyondmthfr.com/2014/05/07/how-to-balance-comt-and-mao-in-the-brain/