My saliva cortisol test showed higher cortisol the hours after taking methyl folate. Why is that? Has enoyone else noticed this correlation? Does it stimulate adrenals or does it just help HPA signalling? According to 23andME I'm a bit sensitive to methyl groups but different kinds of folate always had the same effect on me, no difference between them. My adrenals seem very weak at the moment and I've started crashing the day after having effect from metafolin. Is cortisol the reason it gives energy? This study found a correlation: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847740/ Could folate be bad for adrenals?