im thinking of taking milk thistle for detox. i had a DNA adducts test a year after my ME diagnosis (2008) which showed 1. diamino compound 9 ng/ml - not on any specific gene, usually from hair dye/ other cosmetics. 2. malondialdehyde 25 ng/ml (from lipid peroxidation), 3. nickel 14 ng/ml -on chromosome 21 (probably on zu/cu-sod1 gene) and chromosome 11 (may affect glutathione- peroxidace gene) the ME doctor i was seeing said the MDA (malondialdehyde) is from fat metabolism and usually caused by vitamin C deficiency. my suggested treatment was at least a gram of vit c and to take heel detox kit Lyphosot , Nux vomica-Homaccord, Berberis-Homaccord. specifically this: http://www.heel.ca/upload/Detox_Kit_Patient_Flyer_ANG_June_2009_7293.pdf i did this and had bad migraines whilst taking the detox drops in water but i don't really know what it did other than that. i also took heel hepeel homeopathic tablets for my liver. i found it had no affect on me. anyway, shortly after that my doctor retired so i dont know how effective treatment was as i had no follow up tests. could milk thistle help? i tried it once at the suggestion of a naturopath and it gave me a migraine. is this detox reaction or something else? i also wanted to try it for painful periods as it can get rid of excess hormones. any advice or experience would be grealty appreciated. im not on any meds/supplements.