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Cytokine theory of depression

Discussion in 'Other Health News and Research' started by wastwater, May 29, 2016.

  1. wastwater

    wastwater Senior Member

    ScottTriGuy and seunderwood like this.
  2. stridor

    stridor Senior Member

    Powassan, Ontario
    Perhaps this ties in with the lipopolysaccharide research. LPS are bits of cell wall derived from the constant turnover of gut bacteria. Gut issues lead to leaking of LPS from the intestines and the immune system thinking that it is under attack from a bacterial invader goes nuts.

    Injection of LPS have created near instantaneous depressive and anxiety symptoms. Perhaps this is a by-product of the immune system's response.

    This idea incorporates some of our current thinking on these things. That the gut and brain are dance partners. That many with mental health challenges have identified gut problems and recent work teasing apart the mystery of the gut biome.
    ScottTriGuy likes this.

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