Anyone know whether Motrin, Aleve, aspirin, and Tylenol lower cortisol significantly enough that ME'ers need to be conscious of this when taking NSAIDs? I'm having amalgams removed, and with a good protocol the problem was not stirring up mercury but porcelains that harden in minutes and cause bite issues, muscle / tendon pain, and repeat visits. Softer mercury amalgams took 24 hours to harden and the bite adjusted better! Back to cortisol--literature suggests Omega-3 foods, nuts, kale etc lower cortisol by reducing inflammation and the stress response, and thus the need for cortisol secretion. So would NSAIDs, too, I suppose. But would an an "exogenous replacement" for natural hormone flatten the cortisol curve over time the way steroids, do? I've been on 4,000 mg of Motrin daily for several weeks as this sorts out and it's getting harder and harder to get out of bed--like my first year of ME. And like my onset of ME, the weakness resolves early evening. No difficult sleeping again, yet. Any thoughts? Thanks.