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Concrete evidence of cognitive dysfunction in ME

Discussion in 'Neurological/Neuro-sensory' started by 62milestogojoe, Aug 12, 2017.

  1. 62milestogojoe

    62milestogojoe What's a forum then?

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    You hit the nail on the head. Will do.
     
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  2. 62milestogojoe

    62milestogojoe What's a forum then?

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    Is this part of the chain leading to the neuroinflammation? Autoantibodies reaction? The full thread is under Immunological section in the forums
    [​IMG]
    [​IMG]
     
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  3. lansbergen

    lansbergen Senior Member

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    I have no idea but the immunemodulator levamisole that I use is an allosteric modulator of α7-nAChR.

     
  4. 62milestogojoe

    62milestogojoe What's a forum then?

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    Really interesting lansbergen-have you considered vaping nicotine as an alternative to levamisole? (I vape but only as a 95% safer alternative to smoking).

    If you don't mind me asking, did you choose the drug on the basis of reduction in WBC count or specifically for the 'neuroprotective ' properties?
     
  5. 62milestogojoe

    62milestogojoe What's a forum then?

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    Thanks Hip. I have to say how saddened I was at the causes of death- hell...do we need answers with ME! I noted Chia had generalized infection whereas Richardson et al had much more specific infection with regard to localisation.

    'Dsyfunction of sensory/autonomic nervous system' does not seem to be an altogether unsurprising conclusion...
    BTW my search on Jesse's AAB brought up some interesting facts pertaining to vagus nerve but I thought it best to keep things as simple as possible in the AAB 'atlas' diagram.

    My line of thought here is quite naive: I do not believe health authorities will consider ME with the gravity it deserves until there are definitive tests enabling a diagnosis. As a result, I think we might try to 1- gather evidence for AAB to potentially generate a ME spectrum ELISA screen test and 2 use PET as in Osaka to confirm evidence of neuroinflammation.

    My rationale is also naive: if we can 'prove' clinically that we are very sick people then health authorities will be obliged to begin exploring treatment. Given the current state of affairs, they can effectively sweep us under the carpet, and as your link illustrates-people die as a result.
     
    Hip likes this.
  6. 62milestogojoe

    62milestogojoe What's a forum then?

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    Hi lansbergen. I am interested in trying Levamisole. I think you posted your dose somewhere but I can't find it. Could you tell me your dose please? The drug is relatively cheap which is useful.
     
  7. lansbergen

    lansbergen Senior Member

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    I smoke like a chimney. I need it.
     
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  8. 62milestogojoe

    62milestogojoe What's a forum then?

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    Strength 4 coffee + golden virginia roll ups = bliss
    Did you get my query about Lavamisole dosage?
     
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  9. lansbergen

    lansbergen Senior Member

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    I do not take more than 100mg per day. I need it every day. If I forget I have a huge hangover the next morning. I take it in the evening before going to bed.
     
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  10. 62milestogojoe

    62milestogojoe What's a forum then?

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    Thanks, appreciate it.
     
  11. Frenchguy

    Frenchguy

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    Any update ?
     

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