I regularly get cold flushes in my legs & that is the sign that I am really tired. Even to the point I have to collapse where I stand. No one has ever understood this. Others always talk about hot flushes. Anyone else get cold flushes? The only other time in my life I got cold flushes, before I had CFS, was when I stayed awake all night one when I stayed out overnight as a 14 year old. The cold flushes were a physical nudge from my body to rest.