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Clinical trial looking at manganese inhibiting drugs at Stanford

Discussion in 'Lyme Disease and Co-Infections' started by justy, Aug 17, 2015.

  1. justy

    justy Donate Advocate Demonstrate

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  2. duncan

    duncan Senior Member

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    Interesting study, @justy. Thank you for posting.

    The idiosyncratic way that spirochetes deal with both iron and manganese does seem to suggest dealing with either peculiarity may be a good angle to approach treatment.

    What a curious assortment of scientists that declare themselves part of Bay Area Lyme. Aucott and Branda...Embers and Eshoo - it's a wonder that the universe doesn't collapse into itself, what with their conflicted views & alliances.

    I'd like to be a fly on the wall if ever they all are in the same room at the same time - which I would have to imagine would be via Skype, since they are spread across the expanse of the US.
     
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  3. justy

    justy Donate Advocate Demonstrate

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    @duncan - i'm not familiar with those particular docs, but I did notice Dr Kogelnik is involved, which intrigues me as most M.E researchers seem to deny that Lyme is involved in M.E....wonder if he sees an overlap or keeps it separate?

    I have iron and manganese deficiencies - have decided not to supplement manganese, but hitting the iron right now.
     
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  4. duncan

    duncan Senior Member

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    Kogelnik is involved? I did not see that. Via the Stanford connection, I am assuming.

    I'm sorry, I cannot see where it says that, and I am sure it is right in front of me.
     
    Last edited: Aug 17, 2015
  5. RL_sparky

    RL_sparky Senior Member

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    Update as of August 13, 2015
    The Lyme Clinical trial is currently in review at Stanford University with Principal Investigators: Dr. Safwan Jaradeh (Stanford – Dept of Neurology) and Dr. Andreas Kogelnik (Open Medicine Institute) as well as Dr. Jay Rajadas (Stanford – BioADD Laboratory) around whose work the trial was based.

    http://www.bayarealyme.org/our-research/treatments/clinical-trial/
     
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  6. duncan

    duncan Senior Member

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    Oh, very cool! I'd love to talk to Kogelnik about his and OMI's involvement!
     
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  7. Little Bluestem

    Little Bluestem All Good Things Must Come to an End

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    Christine (Dog Person) said the manganese was needed by the endoplasmic reticulum where iron is processed. I am not sure you will be able to utilize the iron if you are manganese deficient. [But then I am not sure you won't be able to either. I am not knowable on the subject.]
     
  8. justy

    justy Donate Advocate Demonstrate

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    yes I remember that well and I know manganese is important for iron absorption. Problem is I have Lyme and Lyme feeds on Manganese, rather than iron. But thanks for reminding me!
     

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