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Ciclosporin eyedrops make me feel better

Thinktank

Senior Member
Messages
1,640
Location
Europe
I developed severe dry eyes (keratoconjunctivitis sicca) in my first year of ME. Regular eyedrops and ointments did not help so the opthalmologist prescribed me ciclosporin 0.05% eyesdrops, brandname restasis. After a few days i noticed a drop in bodywide inflammation and my brainfog lifted somewhat.
I was afraid of the possible side effects so ceased taking it.

Ciclosporin decreases the function of T-cells and it also has an effect on mitochondria.
I know a 0.05% dose is very low, but i'm very sensitive to medication, even topical preperations usually have a systemic effect on me.

So, might ciclosporin in theory be efficient in ME?

I've also been diagnosed with a Crohns-like disease which ciclosporin is sometimes used for.