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Carnitine results

Discussion in 'Diagnostic Guidelines and Laboratory Testing' started by TaylorV, Feb 7, 2013.

  1. TaylorV

    TaylorV

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    Had some mito tests done and my carnitine esters came back practically non-existent. Carnitine free and total were within range. See below.

    Carnitine esters: 1 (3.8-19.0)
    Carnitine free: 39 (25.0-55.0)
    Carnitine total: 40 (31.0-67.0)

    Does anyone know of the significance of low esters only? Has anyone else had this?

    Thx!
     
  2. Valentijn

    Valentijn Senior Member

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    When people talk about "carnitine esters" they usually mean a specific type called "acylcarnitines". That might be a more useful search term if you want to go looking around more on the internet.

    Low carnitine esters can basically interfere with your ability to metabolize fats and/or carbohydrates, and can cause insulin issues as well.

    Most research in acylcarnitine is looking at excesses, not deficiencies, but here's some regarding CFS patients with deficiencies in acylcarnitine:
    http://www.ncbi.nlm.nih.gov/pubmed/8148455
    http://www.ncbi.nlm.nih.gov/pubmed/9854142
    http://www.cfids-cab.org/cfs-inform/CFStreatment/vermeulen.scholte04.pdf (full text)
    http://www.ncbi.nlm.nih.gov/pubmed/21205027

    The general advice seems to be to supplement some form of carnitine, and the most recent study suggests adding omega-3 (fish oil) to that as well. There's a thread about acylcarnitines on this forum at http://forums.phoenixrising.me/inde...tential-involvement-of-altered-carnitin.8028/
     
  3. TaylorV

    TaylorV

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    Thanks Valentijn! The information you provided was fantastic and very helpful. Way more than I was able to find on my own.

    Thank you again!
     

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