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Biomarker found in 2 CFS onset groups NK cells

Discussion in 'Latest ME/CFS Research' started by Belbyr, Aug 19, 2018.

  1. Belbyr

    Belbyr Senior Member

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  2. ljimbo423

    ljimbo423 Senior Member

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    From the paper-

     
    Last edited: Aug 20, 2018
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  3. alex3619

    alex3619 Senior Member

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    Nancy Klimas found she can restore NK function in the test tube with IL-15.
     
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  4. junkcrap50

    junkcrap50 Senior Member

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    In GWI not CFS/ME, if I recall correctly. But I'll have to go back and double check.
     
  5. alex3619

    alex3619 Senior Member

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    You could be right, I would have to recheck too.

    PS Just rewatched the video presentation segment, and IL-15 was low in both GWI and CFS. She was not specific about which illness had restoration of NK function, she did not distinguish between them on this issue in the video.
     
    Last edited: Aug 20, 2018
  6. bctjr1993

    bctjr1993

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    So would that mean that IL-15 could be a potential treatment for CFS? Or is it like Ron Davis saying that while certain things return the cells to normal, they aren't safe to be given as medications?
     
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  7. alex3619

    alex3619 Senior Member

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    I don't know. In vitro testing is not the same as a clinical trial, and its too early to try this. However this might become a treatment in just a couple of years.
     
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  8. Seven (formerly lnester7)

    Seven (formerly lnester7) Seven

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    Is sounds simple, but Klimas (Peterson, and the whole old crew) knew all along about the NK cells, if we could raise it, we would have done so by now, but since I have been in treatment I have not been able to raise w their current options, so hopefully the break through is in how to raise NK via IL-15 since the other info is very old news.
     
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  9. Wolfcub

    Wolfcub Senior Member

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    Thanks for posting this, @Belbyr I am starting at the bare beginning as have only been unwell just over 5 months. I need to start at the beginning with so many things. So it's helpful.
     
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  10. bertiedog

    bertiedog Senior Member

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    I was thinking the same thing. I have watched some many videos over the years from Nancy Klimas explaining the situation regarding low Natural Killer Cells in ME and the latest video posted here on PR today was all about this again. She seemed to be quite sure though that she had some ideas as what might help them to become more "normal"

    Pam
     
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  11. Shoshana

    Shoshana Northern USA

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    Which 2 CFS onset groups did this possibly include?

    Thank you!
     
  12. hamsterman

    hamsterman Senior Member

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    I'd assume they met sudden onset (ie post-infection) and gradual onset (Autoimmune disease triggered)
     
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  13. Shoshana

    Shoshana Northern USA

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    Ok, thank you @hamsterman
    My thinking was that there are possible or likely, more than 2 sub-groups, so that is why I was confused.

    But those 2 onset types. Ok.
    That helps my thinking.
     
  14. Belbyr

    Belbyr Senior Member

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