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B12 working but can't sleep.....

SanDiego#1

SanDiego#1
Messages
280
Location
SouthEast USA
When you say methylcobalamin injections didn't work do you mean it had no effect or had a bad effect? I've heard anecdotally that the quality of methyl injections is sometimes degraded (possibly due to light exposure?) and I'm just curious how prevalent this is. I've also heard people have good results with methylcobalamin injections.[/quot

Lotus- It did not do anything for me energy or Cognitive wise. CFIDS Dr. said to do Hydroxy everyday 1cc sub Q. Folate mixed with it 2 times a week. Then once a week he wants me to use Cyanacobalamine 1cc-. Which really gives me a great cognitive and Energy lift. I get that IM from nurse. He said the Cyana boosts the Hydroxy and the Folate effect. I will have to say it works. It's like someone clicks o a light bulb 30 min after I do this schedule. I know all the lit on Cyana-but all my tests say my levels are OK. Not sure f any one here is taking enough of the B-12.SamE also is good for Cognitive. Just can't stay on it too long.I keep all of my B-12 in fridge in dark wrappers or bags. It does lose its potency from light.
Warm by holding in syringe before injections.

San Diego #1
 

Lotus97

Senior Member
Messages
2,041
Location
United States
SanDiego#1
If the methylcobalamin injection didn't have an effect on you then it was probably degraded in quality. I didn't realize hydroxy was also light sensitive. I'm glad you got a good batch then. I wouldn't recommend taking cyanocobalamin since it breaks down into cyanide. Luckily for you, hydroxocobalamin helps with cyanide poisoning, but it would probably still be better to take extra hydroxocobalamin injections (or sublingual B12 in addition to the hydroxy injection) rather than cyanocobalamin. Both hydroxocobalamin and cyanocobalamin convert into methylcobalamin and adenosylcobalamin so I don't know why cyano is necessary since hydroxy does the same thing.

Update: I took a few minutes to do some Google searches on whether or not taking cyanocobalamin carries a risk of cyanide poisoning and the answer is less than clear. I'm too tired to look any further so maybe someone who knows whether the risk is real or not will respond. If there wasn't a risk to taking cyanocobalamin then I don't know why Rich would have chosen hydroxocobalamin since hydroxocobalamin is exponentially more expensive than cyanocobalamin.
 

SanDiego#1

SanDiego#1
Messages
280
Location
SouthEast USA
Sometimes people with that reaction to melatonin are taking too high a dose. Some people take less than 1 mg and find that more effective. But you say works well for you and yet it makes your heart race (?)


Just read where you are taking Xylotal to get enough saliva for test. Xylotal is Lethal for anyone that has CFIDS or ME. It is an artificial sweetener. I agree with info on Cyana. I have been checked over and over again. Not taking every week. It is much cheaper than Hydroxy. It all depends on the strength you use.It is also covered by insurance.Everyone has to do what works for them.

San Diego #1
 

Lotus97

Senior Member
Messages
2,041
Location
United States
Just read where you are taking Xylotal to get enough saliva for test. Xylotal is Lethal for anyone that has CFIDS or ME. It is an artificial sweetener. I agree with info on Cyana. I have been checked over and over again. Not taking every week. It is much cheaper than Hydroxy. It all depends on the strength you use.It is also covered by insurance.Everyone has to do what works for them.

San Diego #1
Since you're taking hydroxocobalamin with the cyanocobalamin you're probably ok, but I thought I'd mention it anyway. Maybe you could try a small amount of sublingual methylcobalamin and adenosylcobalamin to augment your hydroxocobalamin injections.

Xylitol is a sugar alcohol, not an artificial sweetener. I do agree that sugar alcohols aren't good to take. Some of my sublinguals have sugar alcohols and one of my protein powders also does, but other than that I mostly use stevia as a sweetener. Of course I'm not convinced that stevia is 100% ok to take. I'm not sure if there's much information saying that stevia is bad, but I'm not sure there's been studies on stevia either so we really don't know if it is safe. As for the xylitol I buy in bulk, I don't use that as a sweetener. I actually use that to make my own saline nasal spray:
http://forums.phoenixrising.me/inde...ay-for-sinus-congestion-sinusitis-save.21430/
 

SanDiego#1

SanDiego#1
Messages
280
Location
SouthEast USA
Since you're taking hydroxocobalamin with the cyanocobalamin you're probably ok, but I thought I'd mention it anyway. Maybe you could try a small amount of sublingual methylcobalamin and adenosylcobalamin to augment your hydroxocobalamin injections.

Xylitol is a sugar alcohol, not an artificial sweetener. I do agree that sugar alcohols aren't good to take. Some of my sublinguals have sugar alcohols and one of my protein powders also does, but other than that I mostly use stevia as a sweetener. Of course I'm not convinced that stevia is 100% ok to take. I'm not sure if there's much information saying that stevia is bad, but I'm not sure there's been studies on stevia either so we really don't know if it is safe. As for the xylitol I buy in bulk, I don't use that as a sweetener. I actually use that to make my own saline nasal spray:
http://forums.phoenixrising.me/inde...ay-for-sinus-congestion-sinusitis-save.21430/

I am Gluten Intolerant and am also seeing a Gluten Specialist. She saw me lick an envelope with this artificial sweetener in it and said she had just sent another patient to the hospital who had done the same thing. I am not Celiac just intolerant. It seems this substance is in everything.Xylitol works the same in your system as any of the other Art sweeteners. I use Stevia also -and am not sure it is OK either.
Cfids Dr. even told me no tropical fruit including bananas as they stay in the GUT and ferment. NO SUGAR or Art Sweet.I can have berries, apples and Pears???????? Does the Nasal Spray work?

Hard to know everything we should not use or take. I have to go by how I feel. Enjoy your posts.
Interesting. !!!!!! Please see my posts on blog on everyone knocking Antidepressants.

San Diego#1
 

Lotus97

Senior Member
Messages
2,041
Location
United States
I was on Flonase and I seem to be doing fine with just the saline nasal spray. I think there might be other factors as to why I'm not experiencing congestion so I don't want to say for sure, but the ingredients are the same as the brands who sell saline sprays. It's much cheaper to make your own. Also, some brands use benzalkonium chloride which can cause rebound congestion when you stop.
 

SanDiego#1

SanDiego#1
Messages
280
Location
SouthEast USA
I was on Flonase and I seem to be doing fine with just the saline nasal spray. I think there might be other factors as to why I'm not experiencing congestion so I don't want to say for sure, but the ingredients are the same as the brands who sell saline sprays. It's much cheaper to make your own. Also, some brands use benzalkonium chloride which can cause rebound congestion when you stop.


Flonase works for me for a day. That is all I can take it. I have Air Purifiers all over the house Austin-however
when you go out-the pollen still bothers me some. I will try the saline. What are your measurements?

San Diego #1
 

Lotus97

Senior Member
Messages
2,041
Location
United States
Flonase works for me for a day. That is all I can take it. I have Air Purifiers all over the house Austin-however
when you go out-the pollen still bothers me some. I will try the saline. What are your measurements?

San Diego #1
I posted the instructions in that thread I linked to in my previous post. If you find it irritating then you might need to add less salt and/or a different kind of salt. Myself and someone else commented on that in the thread. Adding too much grapefruit seed extract will also be irritating.
 
Messages
28
Location
Brandon, MB Canada
I recently switched my b12 from Source Naturals to Enzymatic therapy and although during the day I felt fine at night my legs felt like they were vibrating and I couldn't sleep at all. Why would that be?
 

taniaaust1

Senior Member
Messages
13,054
Location
Sth Australia
Adding too much grapefruit seed extract will also be irritating.

Watch it with the grapeseed extract, it is one of the most common things people react to in natural products.. it may of been listed as the top thing people react to in natural products (where its often used as a natural preservative). My skin has gone into burning with products in which that is in (and it can make me rash).
 

Lotus97

Senior Member
Messages
2,041
Location
United States
Watch it with the grapeseed extract, it is one of the most common things people react to in natural products.. it may of been listed as the top thing people react to in natural products (where its often used as a natural preservative). My skin has gone into burning with products in which that is in (and it can make me rash).
Someone recently told me that the active ingredient in grapefruit extract might actually be some chemical rather than the GSE. I might stop using it myself if this information pans out. There does seem to be research to support that claim.
 

Lotus97

Senior Member
Messages
2,041
Location
United States
I recently switched my b12 from Source Naturals to Enzymatic therapy and although during the day I felt fine at night my legs felt like they were vibrating and I couldn't sleep at all. Why would that be?
Some people experience low potassium from methylation so you might want to supplement with that as well. Just make sure not to take potassium at the same time as the methylfolate because it will block folate absorption.
 
Messages
28
Location
Brandon, MB Canada
Whoops, the brand of sublingual I've been taking is Natural Factors. Lots of good reviews about it on iherb.com. I read that enzymatic therapy was the one to take but I'm switching back.
 

Phred

Senior Member
Messages
141
Someone recently told me that the active ingredient in grapefruit extract might actually be some chemical rather than the GSE. I might stop using it myself if this information pans out. There does seem to be research to support that claim.

Hi Lotus,

I used to have a soaping business and made hand-made lotion, way back in the day. GSE is not a natural preservative. Believe me a NATURAL preservative is the holy grail in the cosmetic industry. The one study where they found GSE to work, they later found that the GSE had been contaminated with parabens. That's what was actually doing the preserving. If GSE worked Revlon, Maybelline, etc would all be using it. Then we wouldn't be having debates on to paraben or not to paraben. There are preservative without parabens, but they have other crap in them that people get uptight about. Personally I'm much more concerned about a staph infection from someone not sterilizing their equipment and work surfaces well enough and then not using a well researched preservative. That's a lot scarier to me.

Sorry, I get a little worked up over this. Far too many in the cottage cosmetic industry are using GSE thinking they are keeping their customers safe from bacteria, mould and yeast when they are not. I fear for what people are unknowingly putting on their skins.
 

Lotus97

Senior Member
Messages
2,041
Location
United States
Whoops, the brand of sublingual I've been taking is Natural Factors. Lots of good reviews about it on iherb.com. I read that enzymatic therapy was the one to take but I'm switching back.

Enzymatic Therapy is supposed to be one of the better brands. Maybe you just need a lower dose of Enzymatic Therapy than Natural Factors since it's possibly more potent.
 
Messages
28
Location
Brandon, MB Canada
I'm actually more then likely absorbing more of the Natural Factors as it was under my tongue unlike the Enzymatic Therapies where I just swallowed it. Both were 1000mcg. Anyway, just thought it was kind of weird that depending on where my body absorbs it I get different reactions.
 

Lotus97

Senior Member
Messages
2,041
Location
United States
I'm actually more then likely absorbing more of the Natural Factors as it was under my tongue unlike the Enzymatic Therapies where I just swallowed it. Both were 1000mcg. Anyway, just thought it was kind of weird that depending on where my body absorbs it I get different reactions.

Oh, ok. I assumed you were taking both sublingually. Do you notice any positive effects from Natural Factors?
 
Messages
28
Location
Brandon, MB Canada
I do but I don't suffer from a lot of the symptoms that I read about here as I figured out pretty fast why I was dizzy and tired. It actually all started from a yeast infection oddly enough. But anyway, I feel pretty good when I take it but if I take too much I can't sleep. Judging by the great reviews of it on iHerb.com I definitely think it's worth trying. I've also been messing around with metafolin but don't want to continue until I get a mthfr test done to make sure I actually need it.