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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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Sorry for what I assume is a bit of an uninformed question. I started up methyl b12 and adeno b12. Had a definite response- neuropathy was way more active. Titrated up to about 4000 methyl and 3000 adeno over 2 months. Never really involved folate. Now, however, even small doses of folate (200) give me a sore throat and headache. Before b12, folate didn't do this. I understand this is a methylation issue and that there are different camps on how to approach this. It seems to me that I probably have to take a few days off or everything and start over with low doses of b12 and folate and titrate them together. Or, how much do I need the folate? I don't have massive fatigue and hundreds of symptoms. I have neuropathy. I realize the suggestion of doing just b12 and no folate must sound ridiculous. Thoughts from experienced people? Thank you.
Hi,
My B12 test reading was 150 . ( April 2016 ) . I am pure vegetarian (No milk, meat.egg etc.) for the last 10 years.
I am 40 yo. male.
Symptoms were feet numbness , unable to focus on anything and could not even get up from bed on most of the days , frequent falls since Oct 2015.
And bowel Incontinence since 2014.
Neuro Doctor suggested cyno Cbl last year , but I discontinued after 2 weeks.
Now again I have started Methyl Cbl after reading this forum this month , and am self injecting 4.5 mg a day of methyl Cbl .( SC injections).
Have found benefits by using methyl Cbl. , Pottasium and methyl folate .
I have some questions regarding B12 injections.
1. How do you carry so many injections when travelling abroad ?
2. How do you wrap them in a foil paper ? (to protect from light )
Thanks.
Thanks, Eastman. It appears that the b12 is way more important for me because this is a neuropathy issue and not an ME/CFS issue. But maybe folate is essential for the methyl b12 to really do it's job. I'll keep trying to add it in.Starting over with low doses of B12 and folate seems a good idea to me. The general rule is to keep folate lower than B12, although I myself don't follow that rule.
I believe there are a number of people on this forum who take B12 without folate.
Maybe you were not using the right one, or maybe you need other supplements to make more effective.Honestly that kind of sucks to hear that if I'd just kept on I might have turned around on B12. I did try it twice with Cheney though. Still its something to keep in mind. Thanks for the illuminating story.
So wird, i thought that thethyl b12 was good for neuropathy and nerve repair, even many Ms doctors use it at high injectable doses.Sorry for what I assume is a bit of an uninformed question. I started up methyl b12 and adeno b12. Had a definite response- neuropathy was way more active. Titrated up to about 4000 methyl and 3000 adeno over 2 months. Never really involved folate. Now, however, even small doses of folate (200) give me a sore throat and headache. Before b12, folate didn't do this. I understand this is a methylation issue and that there are different camps on how to approach this. It seems to me that I probably have to take a few days off or everything and start over with low doses of b12 and folate and titrate them together. Or, how much do I need the folate? I don't have massive fatigue and hundreds of symptoms. I have neuropathy. I realize the suggestion of doing just b12 and no folate must sound ridiculous. Thoughts from experienced people? Thank you.
If it's hard or painful, you likely don't have the right mix of nutrients for you.So wird, i thought that thethyl b12 was good for neuropathy and nerve repair, even many Ms doctors use it at high injectable doses.
I may be wrong, but im thinking if. Readin a thread or some were else that at first its hard or more painfull them later if you go thru you will get the benefit
Best to get tested, see what you're short of, and supplement accordingly, preferably under a knowledgeable doctor's supervision, or at least with some education about methylation under your belt.
Arsenic is the #1 worst toxin and can seriously impact ATP production, causing profound fatigue. Worth getting rid of...Thanks @Learner1. I did a hair mineral analysis last year and tested high in Aluminum (12.5 ppm and range was 0-12) and moderately high arsenic. Lead, mercury, and others were relatively low, although they were still traces. I've never done a formal detox before. Maybe it's the aluminum being excreted?
That sounds like plenty of folate for most people. Some may need more due to genetics, but if you feel fine, stay on course for now. Do plan on some nutrient testing in the future, as you could become short of cofactors you need.Well I'm taking a B-complex now twice a day, which as w400mcg methylfolate, plus I take another daily 1000mcg L-Methylfolate supplement (which I may discontinue as I now may get what I need strictly through the B-complex). So I don't think folate is an issue.
Did you get improvements in symptoms from the chelation? If so, what kinds? Thanks for your advice, I'm definitely going to seek out a Naturopath .