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Another obvious and probably effective means of debasing accessible biofilms is therapeutic ultrasound. It's been used fairly widely on biofilm-infected wounds and ulcers, and to some extent on the paranasal sinuses (maxillary and frontal sinuses).
I've tried it on my chronic sinusitis (I'm diagnosed with CFS, Lyme-like-disease etc but have lifelong sinus problems) and initial results have been very positive - it makes a big difference in only one or two treatments. I now have my own therapeutic ultrasound machine and will use it regularly for a longer period in my next test. Unfortunately ultrasound can't conveniently reach the deeper sinuses, Ethmoid (maybe) and Spenoid (definitely, unless you fire it through the brain and I don't know what effect this might have), but maybe it doesn't matter, or maybe they are less prone to infection, or maybe enough ultrasound does get deep enough?
A few refs, there are others that I can't find now, but most research has been done by only a couple of groups ...
http://www.ncbi.nlm.nih.gov/pubmed/19264415
http://www.ncbi.nlm.nih.gov/pubmed/20053307
http://informahealthcare.com/doi/abs/10.1080/09593980701209360
https://www.jstage.jst.go.jp/article/jpts/20/4/20_4_233/_article
http://www.entauckland.co.nz/sinusitis.html
http://www.sciencedirect.com/science/article/pii/S1836955310700515
I've tried it on my chronic sinusitis (I'm diagnosed with CFS, Lyme-like-disease etc but have lifelong sinus problems) and initial results have been very positive - it makes a big difference in only one or two treatments. I now have my own therapeutic ultrasound machine and will use it regularly for a longer period in my next test. Unfortunately ultrasound can't conveniently reach the deeper sinuses, Ethmoid (maybe) and Spenoid (definitely, unless you fire it through the brain and I don't know what effect this might have), but maybe it doesn't matter, or maybe they are less prone to infection, or maybe enough ultrasound does get deep enough?
A few refs, there are others that I can't find now, but most research has been done by only a couple of groups ...
http://www.ncbi.nlm.nih.gov/pubmed/19264415
http://www.ncbi.nlm.nih.gov/pubmed/20053307
http://informahealthcare.com/doi/abs/10.1080/09593980701209360
https://www.jstage.jst.go.jp/article/jpts/20/4/20_4_233/_article
http://www.entauckland.co.nz/sinusitis.html
http://www.sciencedirect.com/science/article/pii/S1836955310700515