Discussion in 'Antivirals, Antibiotics and Immune Modulators' started by jengonwin, Jul 15, 2016.
Has anyone tried a solid dose? Such as 2TBSP a day from a good brand?
Claimed to be a cureall
Ooh I want to know this too, I'm considering munching a teaspoon of the seed daily for various reasons.
I bought some black onion seed but apparently that is not the same thing? Just a misnomer, amiright?
@Hip have you investigated nigella sativa during your many trials?
It absolutely killed my stomach and digestion for days so beware if you are sensitive, needless to say I had to discontinue. My partner takes it and seems to be beneficial to skin and nails but as for M.E....?
I read someone claiming to have cured their MS with it. Seems pretty crazy but you never know.
A doctor i know uses 2tbsp a day in most of his lyme cases
Funnily enough, 15 years ago, when my health problems first began (with severe IBS and its associated anxiety symptoms), black seed oil was one of the first supplements that I tried. Not because black seed oil is good for IBS, but simply because I happened to be walking past a shop in London which was advertising: "Black seed oil: a remedy for all diseases except death — the prophet Mohammed".
Always amused by hyperbole, I bought some there and then. It did not really help my IBS much, though it slightly reduced my anxiety levels.
One of the main pharmacodynamic effects of black seed oil is its NF-κB inhibition. That can be useful. For example, when I was experimenting with supplements to decrease my very high anxiety levels (anxiety which I believe may be due to brain inflammation), I discovered that supplements or drugs that potently inhibited NF-κB helped to reduce the anxiety.
This is probably because NF-κB inhibition can reduce inflammation, which in turn I think will reduce anxiety, if neuroinflammation is the cause of your anxiety.
NF-κB has been found to be more activated in ME/CFS, which in turn may induce more inflammatory cytokines.
Black seed oil is not the only NF-κB inhibitor supplement, though, there are many others. Some of more potent ones are: curcumin, alpha lipoic acid, grape seed extract and ashwagandha (Withania somnifera).
And if you want a really potent NF-κB inhibitor, then consider the drug sulfasalazine. I found that strong NF-κB inhibition noticeably reduce my anxiety levels, so I was taking sulfasalazine for a while for that purpose, and it worked reasonably well. Though eventually I switched to taking a cocktail of several NF-κB inhibitor supplements, which were almost as effective.
After I later discovered the potent anti-anxiety effects of N-acetyl-glucosamine (NAG), I then mostly dropped the NF-κB inhibition strategy, as NAG and a few other added supplements were sufficient to keep my anxiety in check.
Selfhacked has a page on NF-κB inhibition:
How To Inhibit NF-kB: The Key To Health And Master Control of Inflammation - Selfhacked
Note that black seed oil is also a histone deacetylase (HDAC) inhibitor, so that is another action it has in the body.
Wow @Hip you certainly do not disappoint!
It's supposedly a strong anti-histamine and is highly recommended by the Low Histamine Chef... I used it, based on her recommendation and I liked it, but not enough to warrant the price.. Also, taking a lot of oil is not good for my digestion..
If lowering histamine is your goal, I recommend Solgar Quercetin Complex (also includes bromelain - which is excellent - rosehips, vitamin c, rutin, etc.) much better results, cheaper and no hit to digestion.
I've been taking black seed oil (from Turkey) twice a day for the last six months and my swollen glands have disappeared (finally), I also had ear inflammation which has subsided(finally).. Could be a coincidence though- who knows. It's certainly an acquired taste.\
This is the one I take
@Mij what dose are you taking?
At the 30ml dose that @jengonwin mentioned the oil you use would be $2.70 per day.
Cheap if it makes you well, but not in any other circumstance.
@Richard7 I'm taking one tsp in the morning on an empty stomach, and one tsp at night before bedtime. It's not cheap but I wanted to try something that would help with inflammation and this oil has a lot of references to back it up. I had swollen glands and ears every day for over a year and now they are back to normal.
@ebethc Is black seed oil the exact same thing as "Nigella Sativa" or two different products? What do you notice that it does in your own case as far as an anti-histamine? I am still wanting to add other natural antihistamines or mast cell stabilizers (very carefully with my doctors consent) and had been thinking about trying Mangosteen. Am not familiar with black seed oil until Googling it just now and it comes up as Nigella Sativa.
I take 2000 mg of Quercetin per day (plus the Quercetin in NeuroProtek) and agree it is a phenomenal antihistamine. My MCAS doc endorses it and he is not that big on supplements but he truly believes in Quercetin. I use the Jarrow version plus Twin Labs Quercetin + Vitamin C which is citrus free (but am sure Solgar is great, too)!
I believe that nigella sativa and black seed oil are the same thing.... or, black seed oil is derived from nigella sativa (which are black seeds)
I used the brand Amazing Herbs ... I just checked and it's not that expensive to try... I found that I had to take a LOT, which made it expensive as an ongoing supplement.. plus, too much oil for my tummy ... they make capsules & liquid
BTW - I've found Source Naturals to be the best Mangosteen by FAR... I threw out the Solaray that I bought when S.N. was out of stock... (other Solaray products have been fine). The Source Naturals is also recommended by the Low Histamine Chef
Thanks and that makes sense.
Will check out the link and read up more on this product.
Thanks a lot and had no idea which mangosteen to try. Will check out this link as well!
For nearly a year I have been using Cinnamon leaf oil from Sri Lanka.
A week ago I started with Nigella sativa oil, a teaspoon 2 or 3 times a day. In the next 12 months I will take a combination of both and see if it will have a further positive effect on my energy level. At the moment there is definitely more energy between the Herxheimer reactions but the progress has been slow.
I just ordered amazing herbs black seed oilm
Will start at 1tsp a day. Probably need 2tbsp a day to feel anything
Mine arrived. I took 1tsp. About 45min later i started to feel how i feel from some supplements. Brainfog, dry mouth, fatigue etc. Not sure if it is "die off" or i am sensitive.
Will keep on 1tsp a day
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