I started mb12(E.T 2000mcg), quatrefolic(800mcg), 3x99mg potassium gluconate per day, a week or so ago. I had the initial honeymoon period some others have had, feeling a bit better, less cog fog, and increased libido lasting about two days. After that I felt tired, lethargic etc so I jacked up the quatrefolic for a few days to around 2-4mg. There was no improvement so I stopped the mb12 and quatrefolic ... I decided to up the potassium a lot, as had been suggested. 1L coconut water a day, 6-7 bananas, 5-10 x 99mg potassium gluconate tablets. I thought I felt a little better on the first day doing this, but after that not sure I noticed any improvement. During those high potassium food/supplement days my stools were extremely pale. I stopped the bananas and coconut water but continued to take potassium(this time citrate 5x99mg) for a few days. Today I noticed that I had this weird weak cramp feeling in my thigh, some numbness in my left hand/arm, and my head felt weird and spacy about 1-2 hours after my last potassium dose(2x99mg). I've experienced a similar head spacy feeling following potassium supplementation in the past. I have a feeling it was hyperkalemia. I waited about two hours, drank a lot of water and felt slightly better. I then took some copper and felt much better about 30 minutes to an hour after that, and all the above symptoms went away. Aside from the potassium issue, I believe a lot of my issues revolve around copper. Out of the 100's of supplements I've tried copper has had the most distinct effect. a small dose 150mcg-300mcg can stop a panic attack, make me calmer, improve verbal fluency, sometimes give energy. A couple of times I even noticed a rise in libido afterwards. But I dont seem to improve if I take more, in fact several times in the past I get overexcited by my immediate, positive reaction and try supplementing 0.5-2mg a day for several days. I end up feeling worse (weird feeling in brain, bad mood, mild kidney pain). So I guess the only conclusion from this is that I am both copper toxic and deficient?